AMG 487

Chemical Name:AMG 487
Synonyms:N-[(1R)-1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)benzeneacetamide
CAS Number:473719-41-4
Molecular Formula:C₃₂H₂₈F₃N₅O₄
Molecular Weight:603.59
Category:Standards;
Applications:N-[(1R)-1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)benzeneacetamide is a selective and potent antagonist of the chemokine receptor CXCR3.
References:Tonn, G. R., et al.: Drug Metab Dispos. 37, 502 (2009); Henne, K. R., et al.: Drug Metab Dispos. 40, 1429 (2012)
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