Catalogue Number:A355400Chemical Name:(R,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamideSynonyms:Des(dimethylamino)-Afatinib//Afatinib Impurity HCAS Number:2223677-64-1Molecular Formula:C₂₂H₂₀ClFN₄O₃Molecular Weight:442.88Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:Des(dimethylamino)-Afatinib is an impurity of…

Catalogue Number:A355395Chemical Name:3-Fluoro-AfatinibSynonyms:(E)-4-(dimethylamino)but-2-enoic acidCAS Number:2223677-62-9Molecular Formula:C₂₄H₂₅F₂N₅O₃Molecular Weight:469.49Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:3-Fluoro-Afatinib may be useful in the…

Catalogue Number:A355358Chemical Name:AF-DX 116Synonyms:11-[2-[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one; AF-DX 116; Otenzepad; 11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-oneCAS Number:102394-31-0Molecular Formula:C₂₄H₃₁N₅O₂Molecular Weight:421.54Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;Applications:AF-DX 116…

Catalogue Number:A355355Chemical Name:AF-DX 384Synonyms:N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide;CAS Number:118290-26-9Molecular Formula:C₂₇H₃₈N₆O₂Molecular Weight:478.63Category:Research Tools; Standards; Molecular Biology; Enzyme Activators and Inhibitors;Applications:AF-DX…

Catalogue Number:A355335Chemical Name:Afatinib Impurity AFT-8Synonyms:N-[4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutenamide;CAS Number:2323570-72-3Molecular Formula:C₂₄H₂₇ClFN₅O₄Appearance:White to Off-White SolidMelting Point:>95°C (dec.)Molecular Weight:503.95Storage:4°C, Inert atmosphereSolubility:Chloroform…

Catalogue Number:A355320Chemical Name:Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl (Contained ~8.5% Ethanol)Synonyms:N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine; (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine; Des(4-dimethylamino-2-en-1-oxo)butyl AfatinibCAS Number:314771-76-1Molecular Formula:C₁₈H₁₆ClFN₄O₂Appearance:Light Yellow to Light Beige…

Catalogue Number:A355315Chemical Name:Afatinib DimaleateSynonyms:BIBW 2992MA2; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide (2Z)-2-butenedioate;CAS Number:850140-73-7Alternate CAS #Free Base: 439081-18-2 [B377000]Molecular Formula:C₂₄H₂₅ClFN₅O₃•[C₄H₄O₄]₂Appearance:White to…

Catalogue Number:A355305Chemical Name:(2Z)-AfatinibSynonyms:(S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamideCAS Number:1680184-59-1Molecular Formula:C₂₄H₂₅ClFN₅O₃Appearance:Pale Yellow to Light Yellow SolidMelting Point:>134°C (dec.)Molecular Weight:485.94Storage:-20°CSolubility:DMSO (Slightly), Methanol…

Catalogue Number:A355303Chemical Name:Afatinib-d6Synonyms:(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide-d6; BIBW 2992-d6;CAS Number:1313874-96-2Alternate CAS #unlabelled: 850140-72-6Molecular Formula:C₂₄H₁₉D₆ClFN₅O₃Appearance:White to Pale Yellow SolidMolecular Weight:491.98Storage:-20°CSolubility:DMSO…

Catalogue Number:A355300Chemical Name:AfatinibSynonyms:(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; BIBW 2992;CAS Number:850140-72-6Molecular Formula:C₂₄H₂₅ClFN₅O₃Appearance:White to Pale Yellow SolidMelting Point:>140ºC (dec.)Molecular Weight:485.94Storage:-20°CSolubility:DMSO (Slightly),…