CAS:2223677-64-1|(R,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide

Catalogue Number:A355400
Chemical Name:(R,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
Synonyms:Des(dimethylamino)-Afatinib//Afatinib Impurity H
CAS Number:2223677-64-1
Molecular Formula:C₂₂H₂₀ClFN₄O₃
Molecular Weight:442.88
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Des(dimethylamino)-Afatinib is an impurity of Afatinib ( ). Afatinib is an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
References:Nakao, K., et al.: Sci. Rep., 9, 18202 (2019); Ebert, K, PLoS One, 14, 0223225 (2019)
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Taskcm is committed to providing cost-effective products that facilitate drug delivery with our customers.
Email:sales@ebclink.com