BIRH 414-d5

Chemical Name:BIRH 414-d5
Synonyms:11-Ethyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one-d5; BIRH 414 BS-d5
Molecular Formula:C₁₄H₉D₅N₄O
Molecular Weight:259.32
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Isotope labelled BIRH 414 is an derivative of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine, a highly potent inhibitor of wild-type human immunodeficiency virus type 1. BIRH 414 was also shown to exhibit binding affinity towards HIV-1 reverse transcriptase enzyme.
References:Tavlarakis, A., et al.: Molec. Stimu., 35, 1224 (2009); Singh, J., et al.: Oxidation. Commun., 32, 13 (2009); Rizzo, R.C., et al.: J. Med. Chem., 45, 2970 (2002);
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