Carmofur-d11

Chemical Name:Carmofur-d11
Synonyms:5-Fluoro-N-hexyl-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinecarboxamide-d11; 1-(Hexylcarbamoyl)-5-fluorouracil-d11; 1-(Hexylcarbamyl)-5-fluorouracil-d11; 1-(n-Hexylcarbamoyl)-5-fluorouracil-d11; HCFU-d11; Mifurol-d11; Yamaful-d11
Molecular Formula:C₁₁H₅D₁₁FN₃O₃
Molecular Weight:268.33
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Carmofur-d11 is the isotope labelled analog of Carmofur (C183700); a derivative of 5-Fluorouracil (F596000) which is a potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis.
References:Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 221 (1973); Miyashita, O., et al.: Chem. Pharm. Bull., 29, 3181 (1981); Hansen, R.M., et al.: Cancer Invest., 9, 637 (1991); Singh, V., et al.: Chem. Biol., 22, 63 (2015)
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