CAS:1024583-85-4|N-​[3-​[3-​(2-​Amino-​2-​oxoethyl)​-​1H-​indol-​1-​yl]​propyl]​-​carbamic Acid 1,​1-​Dimethylethyl Ester

Catalogue Number:A616315
Chemical Name:N-​[3-​[3-​(2-​Amino-​2-​oxoethyl)​-​1H-​indol-​1-​yl]​propyl]​-​carbamic Acid 1,​1-​Dimethylethyl Ester
Synonyms:t-Butyl (3-(3-(2-Amino-2-oxoethyl)-1H-indol-1-yl)propyl)carbamate
CAS Number:1024583-85-4
Molecular Formula:C₁₈H₂₅N₃O₃
Appearance:Pale Yellow Solid
Molecular Weight:331.41
Solubility:Methanol
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-​[3-​[3-​(2-​Amino-​2-​oxoethyl)​-​1H-​indol-​1-​yl]​propyl]​-​carbamic Acid 1,​1-​Dimethylethyl Ester is an intermediate in synthesizing Bisindolylmaleimide III Hydrochloride (B448480), a protein kinase C inhibitor and was also shown to exhibit inhibitory activities towards PDK1, an important kinase in the insulin signaling pathway.
References:Jena, N.R., et al.: J. Molec. Model., 18, 631 (2012); Murphy, R.C., et al.: ACS. Med. Chem. Lett., 1, 331 (2010)
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