CAS:1025951-76-1|1-(8-Chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-5-yl)ethanone

Catalogue Number:C367553
Chemical Name:1-(8-Chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-5-yl)ethanone
Synonyms:5-Acetyl-8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo-(b,e)(1,4)-diazepine; Clozapine Impurity; 1-​[8-​chloro-​11-​(4-​methyl-​1-​piperazinyl)​-​5H-​dibenzo[b,​e]​[1,​4]​diazepin-​5-​yl]​ethanone
CAS Number:1025951-76-1
Alternate CAS #
Parent Compound: 5786-21-0
Molecular Formula:C₂₀H₂₁ClN₄O
Appearance:White to Off-White Solid
Melting Point:167-169°C
Molecular Weight:368.86
Storage:-20°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:1-(8-Chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-5-yl)ethanone is an impurity of Clozapine, which is an antipsychotic.
References:Stille, et al: Farnaco, Ed. Prat., 26, 603 (1971), Hane, J.M., et al.: Psychopharmacol. Bull., 24, 62 (1988), Meltzer, H.Y.: J. Clin. Psychiatry, 55, Suppl. B, 47 (1994)
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