CAS:1037592-40-7|O-[(5-Amino-2-phenyl-7-benzoxazolyl)methyl]-3,5-dichloro-L-tyrosine

Catalogue Number:A627340
Chemical Name:O-[(5-Amino-2-phenyl-7-benzoxazolyl)methyl]-3,5-dichloro-L-tyrosine
Synonyms:JPH 203;
CAS Number:1037592-40-7
Molecular Formula:C₂₃H₁₉Cl₂N₃O₄
Appearance:Pale Yellow Solid
Melting Point:191 – 193°C
Molecular Weight:472.32
Storage:-20°C
Solubility:DMF (Slightly, Heated), DMSO (Slightly)
Category:Standards; Enzyme Activators and Inhibitors;
Applications:O-[(5-Amino-2-phenyl-7-benzoxazolyl)methyl]-3,5-dichloro-L-tyrosine is a L-type amino acid transporter 1 (LAT1) specific and potent inhibitor that suppresses proliferation in cancer cell lines.
References:Ueno, S., et al.: J. Pharm. Sci., 131, 110-117 (2016); Toyoshima, J., et al.: J. Pharm. Sci., 102, 3228-3238 (2013);
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