CAS:1042605-24-2|α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol

Catalogue Number:A630740
Chemical Name:α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol
Synonyms:2-Amino-1-(2-(trifluoromethoxy)phenyl)ethanol
CAS Number:1042605-24-2
Molecular Formula:C₉H₁₀F₃NO₂
Molecular Weight:221.18
Category:Building Blocks; Miscellaneous;
Applications:α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol is an analog of α-(Aminomethyl)-3-(trifluoromethoxy)benzenemethanol (A630745); a compound that is used as a reagent in the synthesis of potent and selective ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. It is also used as a reagent in the synthesis of 1-aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.
References:Jarvest, R.L., et al.: Bioorg. Med. Chem. Lett., 15, 2305 (2005); Keith, J.M., et al.: Bioorg. Med. Chem. Lett., 24, 1280 (2014)
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