CAS:10590-10-0|Deacetylcephalothin Lactone

Catalogue Number:D198215
Chemical Name:Deacetylcephalothin Lactone
Synonyms:N-[(5aR,6R)-1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl]-2-Thiopheneacetamide; (5aR-trans)-N-(1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl)-2-Thiopheneacetamide;
Impurity:Cefalotin EP Impurity D
CAS Number:10590-10-0
Molecular Formula:C₁₄H₁₂N₂O₄S₂
Appearance:Off-White to Pale Beige Solid
Melting Point:>190°C (dec.)
Molecular Weight:336.39
Storage:4°C, Hygroscopic
Solubility:Aqueous Base (Slightly), DMSO (Slightly)
Stability
Hygroscopic
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Deacetylcephalothin Lactone (Cefalotin EP Impurity D) is an impurity in the synthesis of Cefalonium (C236800), a first-generation cephalosporin antibiotic used as a long-acting intramammary cerate for infusion of dairy cows.
References:Endo, T.: Kach. Kokin. Kenk., 12, 8 (1991); Berry, E.A. et al.: J. Dairy Sci., 90, 760 (2007); Bradley, A.J. et al.: J. Dairy Sci., 93, 1566 (2010); Shibata, K., et al.: J. Antibiot., 50, 135 (1997);
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