CAS:1073255-46-5|2-Chlorophenyl Cyclopentyl-d9 Ketone

Catalogue Number:C377822
Chemical Name:2-Chlorophenyl Cyclopentyl-d9 Ketone
CAS Number:1073255-46-5
Alternate CAS #
unlabelled: 6740-85-8
Molecular Formula:C₁₂H₄D₉ClO
Appearance:Oil
Molecular Weight:217.74
Solubility:Dichloromethane, Ethyl Acetate
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-Chlorophenyl Cyclopentyl-d9 Ketone is an intermediate in synthesizing (S)-Ketamine-d6 Hydrochloride (K165312), a labelled (S)-Ketamine (K165310, HCl salt) which is the more active enantiomer of the NMDA receptor antagonist and anesthetic agent Ketamine (K165300). 2-Chlorophenyl Cyclopentyl-d9 Ketone is also a labelled analogue of 2-Chlorophenyl Cyclopentyl Ketone (C377820), which is used as a reagent in the preparation of bicyclic and polycyclic aromatic hydrocarbons.
References:Meliska, C.J. et al.: J. Pharmacol Exp. Therap., 212, 206 (1980); Smith, D.J. et al.: Neuropharmacology, 20, 391 (1981); Klockgether-Radke, A.P. et al.: Eur. J. Anaesthesiol., 22, 215 (2005); Zheng, H. et al.: Catal. Lett., 142, 573 (2012); Zhao, Y.-B. et al.: Angew. Chem. Int. Ed., 48, 1849 (2009)
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