CAS:107430-66-0|CD 1530

Catalogue Number:C263155
Chemical Name:CD 1530
Synonyms:4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic Acid; 4-(7-((3r,5r,7r)-Adamantan-1-yl)-6-hydroxynaphthalen-2-yl)benzoic Acid
CAS Number:107430-66-0
Molecular Formula:C₂₇H₂₆O₃
Molecular Weight:398.49
Category:Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:CD 1530 is a retinoic acid receptor γ selective agonist. In combination with bexxarotene, they inhibit murine oral-cavity carcinogensis. It is found to inhibit heterotopic ossification and preserve tendon stem cell characteristics. It is also associated with RAR signalling in asthma.
References:Tang, X., et al.: Proc. Natl. Acad. Sci. U.S.A., 111, 8907 (2014); Shimono, K., et al.: Nat. Med. (N. Y., NY, U. S.), 17, 454 (2012); Webb, S., et al.: Stem Cell Res. Ther., 7, 45/1 (2016); Defnet, A. E., et al.: FASEB J., 35, e22016 (2021)
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