CAS:109883-94-5|Diphenylmethyl (6R,7R)-3-(Chloromethyl)-8-oxo-7-[(phenylmethylene)amino]-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Ester

Catalogue Number:D107565
Chemical Name:Diphenylmethyl (6R,7R)-3-(Chloromethyl)-8-oxo-7-[(phenylmethylene)amino]-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Ester
Synonyms:Diphenylmethyl (6R-trans)-(6R,7R)-3-(Chloromethyl)-8-oxo-7-[(phenylmethylene)amino]-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Ester;
CAS Number:109883-94-5
Molecular Formula:C₂₈H₂₃ClN₂O₃S
Molecular Weight:503.01
Category:Building Blocks; Chiral Molecules;
Applications:Diphenylmethyl (6R,7R)-3-(Chloromethyl)-8-oxo-7-[(phenylmethylene)amino]-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Ester is an intermediate used in the synthesis of 1-[[(6R,7R)-7-Amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methylpyrrolidinium Chloride (A603160), which is an impurity in the synthesis of Cefepime (C242750), a semisynthetic, fourth generation cephalosporin antibiotic. Antibacterial.
References:Khan, N.J., et al.: Antimicrob. Agents Chemother., 26, 585 (1984), Naito, T., et al.: J. Antibiot., 39, 1092 (1986), Okamoto, M.P., et al.: Clin. Pharmacokinet., 25, 88 (1993),
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