CAS:112054-78-1|N-Acetyl-9-(acetylamino)-9-deoxyneuraminic Acid

Catalogue Number:A168005
Chemical Name:N-Acetyl-9-(acetylamino)-9-deoxyneuraminic Acid
Synonyms:5,9-Bis(acetylamino)-3,5,9-trideoxy-D-glycero-D-galacto-2-nonulosonic Acid; 9-Acetamido-9-N-(acetyl)-9-deoxy-D-neuraminic Acid;
CAS Number:112054-78-1
Molecular Formula:C₁₃H₂₂N₂O₉
Appearance:Light Beige to Brown Solid
Melting Point:>110°C (dec.)
Molecular Weight:350.32
Storage:-20°C, Hygroscopic
Solubility:Methanol (Slightly), Water (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
Applications:N-Acetyl-9-(acetylamino)-9-deoxyneuraminic Acid is a synthetic sialic acid analogue and the 9-acetamido derivative of N-Acetylneuraminic Acid (A187000). N-Acetyl-9-(acetylamino)-9-deoxyneuraminic Acid can be used by influenza C virus as a receptor determinant for attachment to cells. Modified erythrocytes containing N-Acetyl-9-(acetylamino)-9-deoxyneuraminic Acid were agglutinated by influenza C virus to the same titer as the 9-O-acetyl analogue but was shown to be resistant to cleavage by the viral acetylesterase.
References:Herrler, G. et al.: Acta Histochem. Supp., 40, 39 (1990); Herrler, G. et al.: Biochem. Biophys. Res. Comm., 216, 821 (1995); Herrler, G. et al.: J. Biol. Chem., 267, 12501 (1992);
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