Catalogue Number:C281108
Chemical Name:(R)-Cetirizine-d4 Dihydrochloride
Synonyms:2-[2-[4-[(R)-(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy-d4]acetic Acid Dihydrochloride; (-)-Cetirizine-d4 Dihydrochloride; Levocetirizine-d4 Dihydrochloride;
CAS Number:1133210-23-7
Alternate CAS #
unlabelled: 130018-77-8
Molecular Formula:C₂₁H₂₃D₄Cl₃N₂O₃
Appearance:White to Off-White Solid
Melting Point:205-208°C (dec.)
Molecular Weight:465.83
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Category:Standards; Chiral Molecules; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Labelled (R)-Cetirizine (C281100). A nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.
References:De Vos, C., et al.: Ann. Allergy, 59, 278 (1987), Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987), Fadel, R., et al.: Clin. Allergy, 17, 373 (1987), Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)
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CAS:1133210-23-7|(R)-Cetirizine-d4 Dihydrochloride
