CAS:1169-20-6|(3β,5α)-3-(Acetyloxy)-pregn-16-en-20-one

Catalogue Number:A188140
Chemical Name:(3β,5α)-3-(Acetyloxy)-pregn-16-en-20-one
Synonyms:3β-(Acetyloxy)-5α-pregn-16-en-20-one; 3β-Acetoxy-5α-pregn-16-en-20-one; 3β-Hydroxy-5α-pregn-16-en-20-one Acetate; NSC 166500; Δ16-Allopregnene-3β-ol-20-one Acetate;
CAS Number:1169-20-6
Molecular Formula:C₂₃H₃₄O₃
Molecular Weight:358.51
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
Applications:(3β,5α)-3-(Acetyloxy)-pregn-16-en-20-one is a Tigogenin derivative used in the synthesis of polyhydroxy steroids; Also, it is an intermediate used in the synthesis of Allopregnenolone (A547105), which acts as a GABAA receptor positive allosteric modulator. It is a metabolite of Progesterone (P755900). s It is also a neuroactive steroid present in the blood and also the brain.
References:Bunyathaworn, P., et al.: Kasetsart J. Nat. Sci., 45, 700-716 (2011); Puja, G. et al.: Neuron, 4, 759 (1990); Belelli, D. et ael. Neurosteroid, 6, 565 (2006); Viapiano, M. et al.: Neurochem. Res., 23, 155 (1998);
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