CAS:117796-52-8|N-Acetyldesloratadine

Catalogue Number:A168470
Chemical Name:N-Acetyldesloratadine
Synonyms:1-[4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl]-ethanone; 1-Acetyl-4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine;
CAS Number:117796-52-8
Molecular Formula:C₂₁H₂₁ClN₂O
Appearance:Off-White to Pale Pink Solid
Melting Point:>61°C (dec.)
Molecular Weight:352.86
Storage:4°C
Solubility:Chloroform (Slightly), Ethyl Acetate (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Acetyldesloratadine is an impurity in the synthesis of Desloratadine (D290250), Nonsedating-type histamine H1-receptor antagonist.
References:Kreutner, W., et al.: Arzneimittel-Forsch., 50, 345 (2000); Salmun, L.M., et al.: Clin. Ther., 22, 613 (2000); Agrawal, D.K., et al.: Expert Opin. Invest. Drugs, 10, 547 (2001);
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