CAS:1181081-71-9|CLP 257

Catalogue Number:C560013
Chemical Name:CLP 257
Synonyms:(5Z)-5-[(4-Fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1-(2H)-pyridazinyl)-4(5H)-thiazolone
CAS Number:1181081-71-9
Molecular Formula:C₁₄H₁₄FN₃O₂S
Molecular Weight:307.34
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:CLP 257 (cas# 1181081-71-9) is a useful research chemical.CLP 257 is a KCC2-selective analog that lowers [Cl-​|i. CLP257 restored impaired Cl-​ transport in neurons with diminished KCC2, which is a K+-Cl- transporter, activity.
References:Gagnon, M., et al.: Nat. Med., 19, 1524 (2013);
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