CAS:118175-11-4|a-Amino-b-methyl-b-sulfino-1H-1,2,3-triazole-1-butanoic Acid

Catalogue Number:A618165
Chemical Name:a-Amino-b-methyl-b-sulfino-1H-1,2,3-triazole-1-butanoic Acid
Synonyms:USP Tazobactam Related Compound A:
CAS Number:118175-11-4
Molecular Formula:C₇H₁₂N₄O₄S
Appearance:White to Light Yellow Solid
Melting Point:>111°C (dec.)
Molecular Weight:248.26
Storage:-20°C, Hygroscopic
Solubility:Aqueous Base (Sparingly), DMSO (Slightly, Heated), Methanol (Slightly)
Stability
Hygroscopic, Unstable in Aqueous Solution, Unstable In Water
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:a-Amino-b-methyl-b-sulfino-1H-1,2,3-triazole-1-butanoic Acid is an impurity in the synthesis of Tazobactam (T010100), b-Lactamase inhibitor, used with b-lactam antibiotics to enhance their effect.
References:Gould, I.M., et al.: Drugs Exp. Clin. Res., 17, 187 (1991), Roland, R.K., et al.: J. Infect. Dis., 4, 226 (2000), Bonomo, R.A., et al.: Biochim. Biophys. Acta, 1547, 196 (2001),
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