CAS:1189988-36-0|Dasatinib-d8 N-Oxide

Catalogue Number:D193612
Chemical Name:Dasatinib-d8 N-Oxide
Synonyms:N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl-d8]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide N-Oxide;
CAS Number:1189988-36-0
Alternate CAS #
unlabelled: 910297-52-8
Molecular Formula:C₂₂H₁₈D₈ClN₇O₃S
Appearance:Off-White to Light Yellow Solid
Melting Point:>195°C (dec.)
Molecular Weight:512.05
Storage:-20°C
Solubility:DMSO (Slightly, Heated), Methanol (Slightly, Heated)
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:The labelled oxidative metabolite of Dasatinib (M5 metabolite). It is a COVID19-related research product.
References:Cashman, J.R., et al.: Chem. Res. Toxicol., 8, 165 (1995), Aasmoe, L., et al.: Toxicol. Appl. Pharmacol., 150, 86 (1998), Galetin, A., et al.: J. Pharmacol. Exp. Ther., 314, 180 (2005), Christopher, L.J., et al.: Drug Metab. Dispos., 36, 1357 (2008),
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