CAS:1198300-79-6|Cerdulatinib (PRT2070)

Catalogue Number:C273000
Chemical Name:Cerdulatinib (PRT2070)
Synonyms:4-(Cyclopropylamino)-2-[[4-[4-(ethylsulfonyl)-1-piperazinyl]phenyl]amino]-5-pyrimidinecarboxamide,
CAS Number:1198300-79-6
Molecular Formula:C₂₀H₂₇N₇O₃S
Appearance:Light Yellow Brown Solid
Melting Point:>211°C (dec.)
Molecular Weight:445.54
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Category:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Cerdulatinib (PRT2070), acts as a novel oral and dual spleen tyrosine kinase (Syk) and janus kinase (JAK) inhibitor. Preferentially selects for JAK inhibitors (JAK1 and JAK3 primarily), preventing cytokine mediated signaling and functional responses varying cell types. Potential anti-cancer agent.
References:Coffey, G. et al.: J. Pharmacol. Exp. Ther., 351, 538 (2014);
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