CAS:1217471-51-6|N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1′-biphenyl]-2-yl]carbonyl]-L-methionine Trifluoroacetate Salt

Catalogue Number:A611953
Chemical Name:N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1′-biphenyl]-2-yl]carbonyl]-L-methionine Trifluoroacetate Salt
Synonyms:(2S)-2-[[(5-[[(2R)-2-Amino-3-sulfanylpropyl]amino][1,1′-biphenyl]-2-yl)carbonyl]amino]-4-(methylsulfanyl)butanoic Acid Trifluoroacetate; FTI-276 Trifluoroacetate; (5-(((R)-2-Amino-3-mercaptopropyl)amino)-[1,1′-biphenyl]-2-carbonyl)-L-methionine Trifluoroacetate
CAS Number:1217471-51-6
Alternate CAS #
170006-72-1
Molecular Formula:C₂₁H₂₇N₃O₃S₂ • C ₂HF₃O₂
Molecular Weight:433.59 + 114.02
Category:Standards; Miscellaneous; Molecular Biology; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1′-biphenyl]-2-yl]carbonyl]-L-methionine Trifluoroacetate Salt is a salt analog of N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1′-biphenyl]-2-yl]carbonyl]-L-methionine (CAS# 170006-72-1), which is a farnesyltransferase inhibitor useful in attenuating nicotine and opioid withdrawal.
References:Moise, I., et al.: Bioorg. Med. Chem. Lett., 26, 3730 (2016); Singh, T. G., et al.: Behav. Pharmacol., 24, 668 (2013); Rehni, A. K., et al.: Neuropharmacology, 71, 19 (2013)
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