CAS:1217749-86-4|Atorvastatin-d5 Lactone

Catalogue Number:A791782
Chemical Name:Atorvastatin-d5 Lactone
Synonyms:5-(4-Fluorophenyl)-2-(1-methylethyl)-N-phenyl-(4-phenyl-d5)-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide; Atorvastatin-d5 δ-Lactone;
CAS Number:1217749-86-4
Alternate CAS #
unlabelled: 125995-03-1
Molecular Formula:C₃₃H₂₈D₅FN₂O₄
Appearance:Off-White to Light Yellow Solid
Melting Point:98-100°C
Molecular Weight:545.66
Storage:-20°C, Inert atmosphere
Solubility:Methanol (Slightly), Ethyl Acetate (Slightly)
Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Labelled Atorvastatin intermediate as inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation.
References:Boyd, R., et al.: J. Clin. Pharmacol., 40, 91, (2000), Bogman, K., et al.: Br. J. Pharmacol., 132, 1183 (2001), Backman, J., et al.: Clin. Pharmacol. Ther., 72, 685 (2002), Kalvass, J., et al.: Drug Metab. Dispos., 35, 455 (2007),
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