CAS:1219739-36-2|AMPK Activator 991

CAS:1219739-36-2|AMPK Activator 991

Catalogue Number:A634308
Chemical Name:AMPK Activator 991
Synonyms:5-[[6-Chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yl]oxy]-2-methylbenzoic Acid; Compound 991; EX 229
CAS Number:1219739-36-2
Molecular Formula:C₂₄H₁₈ClN₃O₃
Appearance:White to Off-White Solid
Melting Point:>211°C (dec.)
Molecular Weight:431.87
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Category:Standards; Enzyme Activators and Inhibitors;
Applications:AMPK Activator 991 is a small benzimidazole derivative that potently activates AMP-activated protein kinase (AMPK) to increase glucose transport in skeletal muscle, with possible applications in treating a variety of metabolic disorders, such as Type 2 diabetes.
References:Lai, Yu-Chiang., et al.: Biochem. J.,460, 363 (2014);
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