CAS:1221897-87-5|2-Amino-acetonitrile-2,2-d2 Hydrochloride

Catalogue Number:A580057
Chemical Name:2-Amino-acetonitrile-2,2-d2 Hydrochloride
Synonyms:2-Amino-acetonitrile-d2 Hydrochloride; Amino-acetonitrile-d2 Monohydrochloride; Glycinonitrile-d2 Monohydrochloride; 2-Aminoacetonitrile-d2 Hydrochloride; Aminoacetonitrile-d2 Hydrochloride; Aminoacetonitrile-d2 Monohydrochloride; Glycinonitrile-d2 Hydrochloride; α-Aminoacetonitrile-d2 Hydrochloride
CAS Number:1221897-87-5
Alternate CAS #
1222011-50-8 / 6011-14-9
Molecular Formula:C₂H₂D₂N₂ • HCl
Appearance:White to Off-White Solid
Melting Point:>140°C (dec.)
Molecular Weight:58.08 + (36.46)
Storage:-20°C
Solubility:DMSO (Slightly), Water (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Isotopic Labeled Analogues; Miscellaneous;
Applications:Isotope labelled Aminoacetonitrile Hydrochloride (A580055), a useful synthetic intermediate. It is a reagent used to synthesize dipeptide nitriles as reversible and potent cathepsin S inhibitors. It can also used to prepare substituted cyclic ureas as possible HIV protease inhibitors.
References:Ward, Y., et al.: J. Med. Chem., 45, 5471 (2002); Wilkerson, W., et al.: J. Med. Chem., 40, 4079 (1997)
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