CAS:1240398-15-5|11-Dehydro Thromboxane B2-d4

Catalogue Number:D230557
Chemical Name:11-Dehydro Thromboxane B2-d4
Synonyms:(5Z)-7-[(2R,3S,4S)-Tetrahydro-4-hydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-6-oxo-2H-pyran-3-yl]-5-heptenoic Acid-d4; 11-Dehydro-TXB2-d4; 11-keto-Thromboxane B2-d4; (5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxo-thromboxa-5,13-dien-1-oic Acid-d4; [2R-[2α(1E,3S*),3β(Z),4β]]-7-[Tetrahydro-4-hydroxy-2-(3-hydroxy-1-octenyl)-6-oxo-2H-pyran-3-yl] 5-Heptenoic Acid-d4;
CAS Number:1240398-15-5
Alternate CAS #
unlabelled: 67910-12-7
Molecular Formula:C₂₀H₂₈D₄O₆
Molecular Weight:372.49
Category:Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Isotope labelled 11-Dehydro Thromboxane B2, a metabolite of Thromboxane that is an in vivo markers of oxidative stress and platelet activation. It is associated with adverse cardiovascular events in Alzheimer’s Disease Anti-inflammatory Prevention Trial (ADAPT).
References:Santilli, F. et al.: J. Am. Coll. Cardiol., 47, 391 (2006); Montine, T.J. et al.: PLoS One, 5, No pp given (2010); Boehm, E. et al.: J. Biol. Chem., 279, 7663 (2004);
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