CAS:124431-80-7|CGS 21680A

Catalogue Number:C291790
Chemical Name:CGS 21680A
Synonyms:CGS 21680 Hydrochloride; 4-[2-[[6-Amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic Acid Hydrochloride;
CAS Number:124431-80-7
Alternate CAS #
Free Base: 120225-54-9
Molecular Formula:C₂₃H₃₀ClN₇O₆
Appearance:White to Light Beige Solid
Melting Point:>122°C (dec.)
Molecular Weight:535.98
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
Applications:Adenosine receptors are related to many diseases such as cardiovascular, autoimmune, and cancer. CGS 21680 is a potent and selective agonist of the adenosine A2A receptor, a member of G protein coupled receptor (1,2,3).
References:(1) Jones, K. R., et al.: Sci Rep. 7, 44816 (2017)
(2) Hutchison, A. J., et al.: J. Pharm. Exp. Ther. 251, 47 (1989)
(3) Hasko, G., et al.: Nat. Rev. Drug Discov. 7, 759 (2008)
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