Catalogue Number:C366605
Chemical Name:(3S)-4-Chloro-3-hydroxybutyronitrile
Synonyms:(3S)-4-Chloro-3-hydroxybutanenitrile; (S)-4-Chloro-3-hydroxybutanenitrile; (S)-(-)-4-Chloro-3-hydroxybutyronitrile; (S)-4-Chloro-3-hydroxybutyronitrile;
CAS Number:127913-44-4
Molecular Formula:C₄H₆ClNO
Appearance:Colourless to Pale Yellow Oil
Molecular Weight:119.55
Storage:4°C, Inert atmosphere
Solubility:Chloroform (Sparingly), Methanol (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:(3S)-4-Chloro-3-hydroxybutyronitrile is used in various organic precursor syntheses. It is used in the synthesis of hydroxypyrrolidinones to by used as carbapenem precursors. Also used in the preparation of atorvastatin (A791750) precursors. Impurity in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.
References:Kanno, O. et al.: Hetero., 53, 173 (2000); Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006); Jiang, C. et al.: Lett. Org. Chem., 9, 520 (2012);
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Taskcm is committed to providing cost-effective products that facilitate drug delivery with our customers.
Email:sales@ebclink.com
