CAS:130370-60-4|Batimastat

Catalogue Number:B118760
Chemical Name:Batimastat
Synonyms:(2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]-butanediamide; [2R-[1(S*),2R*,3S*]]-N4-hydroxy-N1-[2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]-butanediamide; (2S,3R)-5-Methyl-3-[[(αS)-α-(methylcarbamoyl)phenethyl]carbamoyl]-2-[(2-thienylthio)methyl]hexanohydroxamic Acid; BB 94;
CAS Number:130370-60-4
Molecular Formula:C₂₃H₃₁N₃O₄S₂
Appearance:White to Off-White Solid
Melting Point:210-212ºC (dec.)
Molecular Weight:477.64
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Batimastat acts as a matrix metalloproteinase inhibitor in the treatment of various cancers, and pathological occurrences such as arthritis and atherosclerosis.
References:Choi, S. et al.: Bull. Kor. Chem. Soc., 32, 2032 (2011); Yurtsever, Z. et al.: J. Biol. Chem., 287, 42138 (2012); Park, C. et al.: Kor. J. Physiol. Pharm., 15, 115 (2011);
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