CAS:1327173-85-2|(S,S)-meta-nitro-Chloramphenicol

Catalogue Number:C325060
Chemical Name:(S,S)-meta-nitro-Chloramphenicol
Synonyms:2,2-Dichloro-N-[(1S,2S)-2-hydroxy-1-(hydroxymethyl)-2-(3-nitrophenyl)ethyl]acetamide; 2,2-Dichloro-N-((1S,2S)-1,3-dihydroxy-1-(3-nitrophenyl)propan-2-yl)acetamide
CAS Number:1327173-85-2
Molecular Formula:C₁₁H₁₂Cl₂N₂O₅
Appearance:White to Off-White Solid
Melting Point:99 – 101°C (subl.)
Molecular Weight:323.13
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Chiral Molecules; Ephedrine; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines;
Applications:(S,S)-meta-nitro-Chloramphenicol is an analog of Chloramphenicol (C325030), a broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial
References:Berendsen, B.J.A., et. al.: J. Chromatogr. A., 1218, 7331 (2011); Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948); Gottlieb, et al.: J. Bacteriol., 55, 409 (1948); Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1975); Price, A., et al.: J. Antibiot., 43, 118 (1981); Shalit, I., et al.: Drugs, 28, 281 (1984)
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