CAS:1346598-70-6|Desbutyl Dronedarone-d6 Hydrochloride

CAS:1346598-70-6|Desbutyl Dronedarone-d6 Hydrochloride

Catalogue Number:D288878
Chemical Name:Desbutyl Dronedarone-d6 Hydrochloride
Synonyms:N-(2-Butyl-3-(4-(3-(butylamino)propoxy-1,1,2,2,3,3-d6)benzoyl)benzofuran-5-yl)methanesulfonamide Hydrochloride;
CAS Number:1346598-70-6
Alternate CAS #
197431-02-0
Molecular Formula:C₂₇H₃₀D₆N₂O₅S • HCl
Appearance:Off-White to Pale Yellow Solid
Melting Point:>138°C (dec.)
Molecular Weight:506.69 + (36.46)
Storage:4°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Isotopic Labeled Analogues; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Desbutyl Dronedarone-d6 Hydrochloride is the labeled analogue of Desbutyl Dronedarone Hydrochloride (D288875) which is a metabolite of Dronedarone (D679445), a drug used for the treatment of atrial fibrillation and atrial flutter in patients who have suffered cardiac arrhythmias.
References:Singh, B., et al.: J. Cardiovas. Pharmacol., 52, 300 (2008); Hoy, S., et al.: Drugs, 69, 1647 (2009); Hohnloser, S., et al.: New Eng. J. Med., 360, 668 (2009);
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