CAS:1353016-71-3|DBCO-NHS Ester

CAS:1353016-71-3|DBCO-NHS Ester

Catalogue Number:D194965
Chemical Name:DBCO-NHS Ester
Synonyms:11,12-Didehydro-oxo-Dibenz[b,f]azocine-5(6H)-butanoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester
CAS Number:1353016-71-3
Molecular Formula:C₂₃H₁₈N₂O₅
Appearance:White to Off-White Solid
Melting Point:>150°C (dec.)
Molecular Weight:402.4
Storage:-20°C, Inert atmosphere
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability
Moisture Sensitive
Category:Building Blocks; Miscellaneous;
Applications:DBCO-NHS Ester is a derivative of DBCO (Dibenzylcyclooctyne), used in Cu-free click chemistry. It useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. Used in DNA-Assisted protein analysis such as proximity ligation and extention assays. Intracellular Imaging.
References:Junhong, Y. et al.: PLOS. One., 9, e108061 (2014); Murrey, H. et al.: J. Am. Chem. Soc., 137, 11461 (2015);
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