CAS:1356019-48-1|(R)-2-Amino-2-[(5-fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate, Trifluoroacetic Acid Salt

Catalogue Number:A609615
Chemical Name:(R)-2-Amino-2-[(5-fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate, Trifluoroacetic Acid Salt
Synonyms:MTSEA-Fluorescein Trifluoroacetic Acid Salt
CAS Number:1356019-48-1
Alternate CAS #
freebase: 1356019-47-0
Molecular Formula:C₂₆H₂₁F₃N₂O₁₀S₂
Appearance:Yellow to Orange Solid
Melting Point:>130°C (dec.)
Molecular Weight:642.58
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Light/Moisture Sensitive; Desiccate And Store at -20°C, Light/Moisture Sensitive
Category:Standards; Fluorescent Reagents; Sulfhydryl Active Reagents;
Applications:A thiol specific fluorescent probe useful for ion channel and protein topology research. The recently available MTS-fluorophores may find application in the real-time monitoring of conformational changes, since fluorophores coupled to introduced cysteines can change their fluorescence during a conformational change. Fluorescence lifetime may also yield information regarding distances and molecular motion in a protein molecule.Fluorescence: max. Abs. 492nm
References:Mannuzzu, L.M., et al.: Science, 271, 213 (1996), Goulett, C.C., et al.: JBC, 273, 45, 30012 (1998), Adams, C.M., et al.: JBC, 273, 46, 30204 (1998)
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