CAS:135704-06-2|CI-992

Catalogue Number:C432725
Chemical Name:CI-992
Synonyms:N-(4-morpholinylsulfonyl)-L-phenylalanyl-3-(2-amino-4-thiazolyl)-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-alaninamide; [1S-(1R*,2S*,3R*)]- N-(4-morpholinylsulfonyl)-L-phenylalanyl-3-(2-amino-4-thiazolyl)-N-[1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-alaninamide; PD 134672;
CAS Number:135704-06-2
Molecular Formula:C₃₃H₅₂N₆O₇S₂
Molecular Weight:708.93
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:CI-992, is a novel potent orally active renin inhibitor, that has been proved to be effective on blood pressure on normotensive and hypertensive monkeys. It is also a derivative of Zankiren (Z148060).
References:Ryan, M. J., et al.: J. Pharmaco. Exp. Therap., 268, 372 (1994);
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