CAS:1360460-82-7|Anlotinib Dihydrochloride

Catalogue Number:A678535
Chemical Name:Anlotinib Dihydrochloride
Synonyms:1-[[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-quinolinyl]oxy]methyl]cyclopropanamine Hydrochloride (1:2); AL3818 Dihydrochloride
CAS Number:1360460-82-7
Alternate CAS #
HCl: 1058156-90-3
Molecular Formula:C₂₃H₂₂FN₃O₃ • 2HCl
Appearance:Off-White to Pale Brown Solid
Melting Point:>252°C (dec.)
Molecular Weight:407.44 + 2(36.46)
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Anlotinib Dihydrochloride, is a novel inhibitor of tyrosine kinase that is designed to primarily inhibit VEGFR2/3, FGFR1-4, PDGFRa/b, c-Kit, and Ret.
References:Sun, Y. et al.: J Hematol Oncol. 2016 Oct 4;9(1):105; Taurin, S. et al.: Int J Gynecol Cancer. 2018 Jan;28(1):152-160;
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