CAS:1374033-38-1|4-[(2-Chloroethyl)amino]-N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine Methyl Ester

Catalogue Number:C363825
Chemical Name:4-[(2-Chloroethyl)amino]-N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine Methyl Ester
CAS Number:1374033-38-1
Molecular Formula:C₁₇H₂₅ClN₂O₄
Appearance:Off-White Solid
Melting Point:72-74ºC
Molecular Weight:356.84
Storage:4°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Category:Building Blocks; Chiral Molecules;
Applications:4-[(2-Chloroethyl)amino]-N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine Methyl Ester is an intermediate in the synthesis of metabolites of Melphalan (M216900), a chemotherapy drug that chemically alters DNA through alkylation of the DNA nucleotide guanine which results in linkages to occur between strands.
References:Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966); Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980)
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