CAS:13815-62-8|4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride

Catalogue Number:C364430
Chemical Name:4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride
Synonyms:4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Monohydrochloride; p-Chloro-benzoic Acid 1-(p-Methoxyphenyl)hydrazide Monohydrochloride
CAS Number:13815-62-8
Molecular Formula:C₁₄H₁₄Cl₂N₂O₂
Appearance:White to Off-White Solid
Melting Point:154 – 156°C
Molecular Weight:313.18
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Miscellaneous;
Applications:4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride is a derivative of (4-Methoxyphenyl)hydrazine Hydrochloride (M265880). It is a useful synthetic intermediate for the preparation of Indomethacin (I641000); a potent, time-dependent, nonselective inhibitor of the cyclooxygenase enzymes COX-1 and COX-2.
References:Blobaum, Anna L., et al.: ACS Med. Chem. Lett., 4(5), 486-490 (2013); Prusakiewicz, Jeffery J., et al.: Biochemistry, 43(49), 15439-15445 (2004)
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