CAS:1385020-40-5|(2S)-2-(3-Aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide Hydrochloride

Catalogue Number:A628328
Chemical Name:(2S)-2-(3-Aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide Hydrochloride
Synonyms:ARRY 520 Hydrochloride; Filanesib Hydrochloride;
CAS Number:1385020-40-5
Alternate CAS #
Free Base: 885060-09-3
Molecular Formula:C₂₀H₂₂F₂N₄O₂S • (HCl)
Appearance:Light Green to Very Dark Green Solid
Melting Point:>92°C (dec.)
Molecular Weight:420.48 + (36.46)
Storage:-20°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Very Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(2S)-2-(3-Aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide Hydrochloride is a known potent kinesin spindle protein inhibitor.
References:Kim, et al.: J. Transl. Med., 7 63 (2009); Woessner, et al.: Anticancer. Res., 29, 4373 (2009); Tunquist, et al.: Mol. Cancer. Ther., 9, 2046 (2010);
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