Catalogue Number:B106500
Chemical Name:Bacitracin (>80%)
Synonyms:N-[[(4R)-2-[(1S,2S)-1-Amino-2-methylbutyl]-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucyl-D-α-glutamyl-L-isoleucyl-L-lysyl-D-ornithyl-L-isoleucyl-D-phenylalanyl-L-histidyl-D-α-aspartyl-L-asparagine (10→4)-Lactam;
CAS Number:1405-87-4
Molecular Formula:C₆₆H₁₀₃N₁₇O₁₆S
Appearance:Pale Yellow Solid
Melting Point:212-214°C (dec.)
Molecular Weight:1422.69
Storage:4°C
Solubility:Aqueous Acidic (Slightly), Methanol (Slightly)
Category:Standards; Amino Acids; Amino Acids/Peptides; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
Applications:Bacitracin Zinc is a peptide antibiotic effective against gram-postive bacteria. Bacitracin is an inhibitor of peptidoglycan synthesis. Bacitracin disrupts bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate. Bacitracin also strongly inhibits proline endopeptidase from human muscle.
References:Ward, J.B. et al.: Biochem. J., 141, 227 (1974); Anastasi, A. et al.: Biochem. J., 290, 601 (1993); Daly, D.J. et al.: Biochem. Soc. Trans., 13, 1161 (1985); Weinberg, E.D. et al.: Antibiot. Ber., 90, (1967);
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Posted inMaterials
CAS:1405-87-4|Bacitracin (>80%)
