CAS:14158-66-8|cis-Clomiphene Hydrochloride

Catalogue Number:C587030
Chemical Name:cis-Clomiphene Hydrochloride
Synonyms:(Z)-2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy]-triethylamine Hydrochloride; 2-[4-[(1Z)-2-Chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethyl-ethanamine Hydrochloride; (Z)-Clomiphene Hydrochloide; RMI 16312; Zuclomifene Hydrochloride; Zuclomiphene Hydrochloride; cis-Clomifene Hydrochloride;
CAS Number:14158-66-8
Alternate CAS #
Free Base: 15690-55-8
Molecular Formula:C₂₆H₂₉Cl₂NO
Appearance:White to Off-White Solid
Melting Point:147-152°C
Molecular Weight:442.42
Storage:-20°C, Inert atmosphere, Light sensitive
Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Cis isomer of Clomiphene (C587025). Found to be antiestrogenic and a less potent inhibitor of LH secretion than the trans isomer.
References:Robert, B.S.: J. Anim. Sci., 33, 607 (1971); Weissenberg, R.: Andrologia, 24, 162 (1992); Palopoli, F.P., J. Med. Chem., 10, 84 (1967); Ernst., et al.: J. Pharm. Sci., 65, 148 (1976); Baustian, C.L., et al.: Pharm. Biomed. Anal., 4, 237 (1986); Schally, A.V., et al.: Vitam. Horm., 30, 146 (1973)
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