CAS:141644-91-9|(5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone

Catalogue Number:A617575
Chemical Name:(5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone
Synonyms:5-Amino-2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]benzofuran
CAS Number:141644-91-9
Molecular Formula:C₃₀H₄₂N₂O₃
Appearance:Dark Orange to Very Dark Orange Oil to Thick Oil
Molecular Weight:478.67
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Miscellaneous;
Applications:(5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone is an intermediate used in the synthesis of dronedarone hydrochloride (I), a class III antiarrhythmia drug for the prevention of cardiac arrhythmias such as atrial fibrillation.
References:Mali, A. C., et al.: Org. Proc. Res. Dev., 17, 863 (2013)
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