CAS:141854-21-9|4′-O-Demethyl-pantoprazole sulfide

Catalogue Number:D232400
Chemical Name:4′-O-Demethyl-pantoprazole sulfide
Synonyms:2-[[[6-(Difluoromethoxy)-1H-benzimidazol-2-yl]thio]methyl]-3-methoxy-4-pyridinol
CAS Number:141854-21-9
Molecular Formula:C₁₅H₁₃F₂N₃O₃S
Appearance:Off-White to Pale Brown Solid
Melting Point:>191.52°C (dec.)
Molecular Weight:353.34
Storage:-20°C
Solubility:DMSO (Sparingly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4′-O-Demethyl-pantoprazole sulfide is an impurity of pantoprazole (P190003), a proton-​pump inhibitor and used to treat gastroesophageal reflux disease, as well as Zollinger-​Ellison syndrome (when the stomach produces too much stomach acid).
References:Peng, C.C., et al.: Handbook of Metabolic Pathways of Xenobiotics, 5, 1953-56 (2014);
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