CAS:1421373-65-0|AZD 9291(Osimertinib)

Catalogue Number:A808075
Chemical Name:AZD 9291(Osimertinib)
Synonyms:N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide; AZD9291; Osimertinib; Tagrisso
CAS Number:1421373-65-0
Molecular Formula:C₂₈H₃₃N₇O₂
Appearance:Pale Yellow to Beige Solid
Melting Point:>188°C (dec.)
Molecular Weight:499.61
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:AZD 9291 is a selective EGFR inhibitor (epidermal growth factor receptor), used in the treatments of nonsmall-cell lung cancer (NSCLC).
References:Finlay, M.R.V., et al.: J. Med. Chem., 57, 8249 (2014);
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