CAS:1422435-41-3|Dabigatran Carboxamide Ethyl Ester

Catalogue Number:D100170
Chemical Name:Dabigatran Carboxamide Ethyl Ester
Synonyms:N-[[2-[[[4-(Aminocarbonyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine Ethyl Ester; Dabigatran Etexilate Mesylate Impurity B
CAS Number:1422435-41-3
Molecular Formula:C₂₇H₂₈N₆O₄
Appearance:White to Off-White Solid
Melting Point:>150°C
Molecular Weight:500.55
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Dabigatran Carboxamide Ethyl Ester is an impurity of Dabigatran Etexilate Mesylate (D100150) which is a nonpeptide, direct thrombin inhibitor.
References:Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002); Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002); Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005)
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