CAS:1431697-94-7|(±)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine Hydrochloride

Catalogue Number:C602023
Chemical Name:(±)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine Hydrochloride
Synonyms:rac-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine Hydrochloride rac-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine Hydrochloride
CAS Number:1431697-94-7
Alternate CAS #
Free Base: 616201-80-0 Anhydrous Free Base: 616202
Molecular Formula:C₁₁H₁₄ClN • HCl
Appearance:White to Off-White Solid
Melting Point:>198°C (dec.)
Molecular Weight:195.69 + (36.46)
Storage:-20°C
Solubility:Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Chiral Molecules; Miscellaneous;
Applications:(±)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine Hydrochloride Hemihydrate is used to prepare and study structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity.
References:Smith, B., et al.: J. Med. Chem., 51, 305 (2008);
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