CAS:144060-84-4|Febuxostat Isopropyl Isomer Ethyl Ester

CAS:144060-84-4|Febuxostat Isopropyl Isomer Ethyl Ester

Catalogue Number:A981375
Chemical Name:Febuxostat Isopropyl Isomer Ethyl Ester
Synonyms:Ethyl 2-(3-Cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylate
CAS Number:144060-84-4
Molecular Formula:C₁₇H₁₈N₂O₃S
Appearance:Off-White to Pale Yellow Solid
Melting Point:131°C
Molecular Weight:330.4
Storage:-20°C, Inert atmosphere
Solubility:Acetonitrile (Slightly), Chloroform (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Febuxostat Isopropyl Isomer Ethyl Ester is an intermediate for the synthesis of Febuxostat Isopropyl Isomer (F229045), which is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor.
References:Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)
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