CAS:1443421-68-8|N6-Cyclopropyl-9-[(1R,4S)-4-[(1,1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-9H-purine-2,6-diamine

Catalogue Number:C989915
Chemical Name:N6-Cyclopropyl-9-[(1R,4S)-4-[(1,1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-9H-purine-2,6-diamine
Synonyms:Abacavir EP Impurity F; Abacavir Impurities
Impurity:Abacavir EP Impurity F
CAS Number:1443421-68-8
Molecular Formula:C₁₈H₂₆N₆O
Appearance:Pale Orange to Light Orange Solid
Melting Point:129-130°C
Molecular Weight:342.44
Storage:4°C, Inert atmosphere
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Chiral Molecules;
Applications:N6-Cyclopropyl-9-[(1R,4S)-4-[(1,1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-9H-purine-2,6-diamine (Abacavir EP Impurity F) is an impurity of Abacavir (A104990), a guanosine analog that inhibits reverse transcriptase (NRTI) (1,2).
References:(1) Hanumegowda, U., et al.: Chem. Res. Toxicol., 23, 749 (2010)
(2) Prasse, C., et al.: Environ. Sci. Technol., 44, 1728 (2010)
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