CAS:147404-76-0|1-​[[2′-​(Aminocarbonyl)​[1,​1′-​biphenyl]​-​4-​yl]​methyl]​-​2-​ethoxy-1H-​benzimidazole-​7-​carboxylic Acid Methyl Ester

Catalogue Number:A147405
Chemical Name:1-​[[2′-​(Aminocarbonyl)​[1,​1′-​biphenyl]​-​4-​yl]​methyl]​-​2-​ethoxy-1H-​benzimidazole-​7-​carboxylic Acid Methyl Ester
Synonyms:Methyl 1-((2′-Carbamoyl-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
CAS Number:147404-76-0
Molecular Formula:C₂₅H₂₃N₃O₄
Appearance:White to Off-White Solid
Melting Point:193-195°C
Molecular Weight:429.47
Storage:4°C, Inert atmosphere
Solubility:Dichloromethane (Slightly), DMSO (Slightly)
Category:Research Tools; Molecular Biology;
Applications:1-​[[2′-​(Aminocarbonyl)​[1,​1′-​biphenyl]​-​4-​yl]​methyl]​-​2-​ethoxy-1H-​benzimidazole-​7-​carboxylic Acid Methyl Ester is an intermediate in the synthesis of Degadant-3 (D229206), which is an intermediate used in the preparation of azilsartan kamedoxomil for use as an angiotensin II receptor blocker. Azilsartan Impurity.
References:Garaga, S., et al.: Org. Process Res. Dev., 19, 514 (2015); Sethi, M. K., et al.: Pharma Chemica, 7, 20 (2015)
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