CAS:147582-55-6|Alcaftadine Methylhydroxy-N-demethylated

Catalogue Number:A514525
Chemical Name:Alcaftadine Methylhydroxy-N-demethylated
Synonyms:Alcaftadine Impurity 1; (11-(Piperidin-4-ylidene)-6,11-dihydro-5H-benzo[d]imidazo[1,2-a]azepin-3-yl)methanol
CAS Number:147582-55-6
Alternate CAS #
147084-10-4
Molecular Formula:C₁₉H₂₃N₃O
Molecular Weight:295.38
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Alcaftadine methylhydroxy-N-Demethylated is the reduced analogue of Alcaftadine (A514530). Alcaftadine is a H1 histamine receptor antagonist. Alcaftadine is used to prevent eye irritation and treat the signs and symptoms of allergic conjunctivitis.
References:Greiner, J.V. et al.: Clin. Ophthamol., 5, 87 (2011); Torkildsen, G. et al.: Curr. Med. Res. Opin., 27, 623 (2011); Bohets, H. et al.: J. Ocular Pharmcol. Therap., 27, 187 (2011);
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