CAS:148436-63-9|AH 13205

Catalogue Number:A434600
Chemical Name:AH 13205
Synonyms:(1R,2S)-2-[4-(1-Hydroxyhexyl)phenyl]-5-oxo-cyclopentaneheptanoic Acid
CAS Number:148436-63-9
Molecular Formula:C₂₄H₃₆O₄
Molecular Weight:388.54
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:AH 13205 is a selective prostanoid EP2-receptor agonist and is known to exhibit neuroprotective properties. Competes with PGE2, Prostaglandin E2 for binding, Prostanoid Receptor agonist. Showed promising activity in guinea pigs but was not effective to show bronchodilator activity in humans.
References:Guan Y, et al. 2002. BMC Pharmacol. Jun 27;2:14
Hillock CJ, et al. 1999. Eur J Pharmacol. 1999 Jul 28;378(1):99-108
Nials AT, et al. 1993. Cardiovasc Drug Rev;11:165–79
James B, et al. 2011. Thorax. Dec; 66(12): 1029–1035
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